Article
Side population does not define stem cell-like cancer cells in the adrenocortical carcinoma cell line NCI h295R.
Endocrinology - 1 Mar 2008
Lichtenauer Urs D, Shapiro Igor, Geiger Klaus, Quinkler Marcus, Fassnacht Martin, Nitschke Roland, Rückauer Klaus-Dieter, Beuschlein Felix
Abstract excerpt
Recent evidence suggests the existence of a stem cell-like subpopulation of cells in hematological and solid tumor entities, which determine the malignant phenotype of a given tumor through their proliferative potential and chemotherapy resistance. A recently used technique for the isolation of this cell population is through exclusion of the vital dye Hoechst 33342, which defines the so-called side population...
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