Liver fattening during feast and famine: an evolutionary paradox.

doi:10.1016/j.mehy.2007.10.006

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Article

Liver fattening during feast and famine: an evolutionary paradox.

Medical hypotheses - 1 Jan 2008

van Ginneken Vincent J T

Abstract excerpt

Liver disease is one of the features of metabolic syndrome, one of the most occurring diseases of the twenty-first century. During food deprivation and starvation, adipose tissue elsewhere in the body delivers lipid components to the liver where they are stored as triacylglycerols (TG). Continuous and excessive food intake, on the other hand, leads to liver fattening (hepatic steatosis). In the long term this...

Topics

Adipose Tissue
Biological Evolution
Body Composition
Eating
Energy Metabolism
Fatty Liver
Food Deprivation
Genotype
Humans
Inflammation
Liver Extracts
Macrophages
Models, Biological
Triglycerides

Source

Open in PubMed

Identifiers

PMID: 18054439
DOI: 10.1016/j.mehy.2007.10.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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