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Article

Direct maximum parsimony phylogeny reconstruction from genotype data.

BMC bioinformatics - 5 Dec 2007

Sridhar Srinath, Lam Fumei, Blelloch Guy E, Ravi R, Schwartz Russell

Abstract excerpt

BACKGROUND: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in population genetics, whole genome analysis, and the search for genetic predictors of disease. Efficient methods are available for reconstruction of maximum parsimony trees from haplotype data, but such data are difficult to determine...

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Identifiers

PMID: 18053244
DOI: 10.1186/1471-2105-8-472
PMCID: PMC2222657

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