Article
The effect of complement factor H Y402H polymorphism on the outcome of photodynamic therapy in age-related macular degeneration.
European journal of ophthalmology - 1 Jan 2000
Seitsonen S P, Jarvela I E, Meri S, Tommila P V, Ranta P H, Immonen I J
Abstract excerpt
PURPOSE: Photodynamic therapy (PDT) has been widely used in the treatment of age-related macular degeneration (AMD). The complement cascade has an important role in the tissue reactions occurring after PDT. The Y402H polymorphism of the complement factor H (CFH) gene has been identified as a risk factor for AMD. Since CFH is central in the regulation of the complement system the authors wanted to analyze whether...
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