Article
Association of hypertension genotypes and decline in renal function after kidney transplantation.
Transplantation - 27 Nov 2007
Israni Ajay K, Li Na, Sidhwani Sonal, Rosas Sylvia, Kong Xiaoxiao, Joffe Marshall, Rebbeck Timothy, Feldman Harold I
Abstract excerpt
BACKGROUND: Polymorphisms of genes such as angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin receptor type I (AGTR1) have been associated with hypertension. Hypertension, in turn, has been associated with decreased renal allograft survival. Therefore, this study investigated whether single nucleotide polymorphisms (SNPs) in these genes are associated with decline in renal function...
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