Article
Genetic polymorphisms and the risk of accelerated renal function decline in women.
PloS one - 1 Jan 2009
Cooper Worobey Cynthia, Fisher Naomi D L, Cox David, Forman John P, Curhan Gary C
Abstract excerpt
BACKGROUND: Reduced glomerular filtration rate is an important predictor of cardiovascular disease and death. Genetic polymorphisms, particularly in genes involved in the renin-angiotensin system (RAS), may influence the rate of renal function decline. METHODOLOGY/PRINCIPAL FINDINGS: We examined the relation between specific single nucleotide polymorphisms (SNPs), including those in the RAS, apolipoprotein E and...
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