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Article

Haptoglobin genotype and renal function decline in type 1 diabetes.

Diabetes - 1 Dec 2009

Costacou Tina, Ferrell Robert E, Ellis Demetrius, Orchard Trevor J

Abstract excerpt

OBJECTIVE: Haptoglobin (Hp) binds free Hb, inhibiting Hb-induced oxidative damage. As oxidative stress has been associated with microvascular complications, we evaluated the relationship between Hp genotype and microalbuminuria, macroalbuminuria, end-stage renal disease (ESRD), and early renal function decline in type 1 diabetes. RESEARCH DESIGN AND METHODS: Participants from the Epidemiology of Diabetes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19720796
DOI: 10.2337/db09-0874
PMCID: PMC2780877

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