Article
Genotype-phenotype correlation for pulmonary function in cystic fibrosis.
Thorax - 1 Jul 2005
de Gracia J, Mata F, Alvarez A, Casals T, Gatner S, Vendrell M, de la Rosa D, Guarner L, Hermosilla E
Abstract excerpt
BACKGROUND: Since the CFTR gene was cloned, more than 1000 mutations have been identified. To date, a clear relationship has not been established between genotype and the progression of lung damage. A study was undertaken of the relationship between genotype, progression of lung disease, and survival in adult patients with cystic fibrosis (CF). METHODS: A prospective cohort of adult patients with CF and two CFTR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.