Article
Issues in association mapping with high-density SNP data and diverse family structures.
Genetic epidemiology - 1 Jan 2007
Bickeböller Heike, Goddard Katrina A B, Igo Robert P, Kraft Peter, Lozano Jingky P, Pankratz Nathan, Balavarca Y, Bardel C, Charoen P, Croiseau P, Guo C-Y, Joo J, Köhler K, Madsen A, Malzahn D, Monsees G, Sohns M, Ye Z
Abstract excerpt
Genetic association studies have the potential to identify causative genetic variants with small effects in complex diseases, but it is not at all clear which study designs best balance power with sample size, especially when taking into account the difficulty of obtaining a sample of the necessary structure. The 14 contributions from the Genetic Analysis Workshop 15 group 3 used data sets with rheumatoid...
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