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Article

Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination.

Atherosclerosis - 1 Jul 2008

Bielinski Suzette J, Pankow James S, Foster Catherine Leiendecker, Miller Michael B, Hopkins Paul N, Eckfeldt John H, Hixson Jim, Liu Yongmei, Register Tom, Myers Richard H, Arnett Donna K

Abstract excerpt

Atherogenesis is a chronic inflammatory process in which intercellular adhesion molecule 1 (ICAM-1) plays a critical role. Circulating soluble ICAM-1 (sICAM-1) is thought to be the result of cleavage of membrane-bound ICAM-1 and its concentration in serum/plasma has been shown to be heritable. Genome-wide linkage scans were conducted for quantitative trait loci influencing sICAM-1. Phenotype and genetic marker...

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Identifiers

PMID: 18045607
DOI: 10.1016/j.atherosclerosis.2007.10.006
PMCID: PMC2517220

Genes

ICAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: the NHLBI Family Heart Study follow-up examination.PMID 18045607Read ↗

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