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Article

Association between NF-κB Pathway Gene Variants and sICAM1 Levels in Taiwanese.

PloS one - 1 Jan 2017

Wu Semon, Teng Ming-Sheng, Er Leay-Kiaw, Hsiao Wan-Yi, Hsu Lung-An, Yeh Ching-Hua, Lin Jeng-Feng, Lin Yi-Ying, Su Cheng-Wen, Ko Yu-Lin

Abstract excerpt

Intercellular adhesion molecule-1 (ICAM1) is crucial to the development and progression of atherosclerosis. Recent genome-wide association studies (GWAS) have revealed that single nucleotide polymorphisms (SNPs) in two of the nuclear factor-κB (NF-κB) pathway genes, NFKBIK and RELA, are associated with soluble ICAM1 (sICAM1) levels. However, neither of these two gene variants is found in the Asian populations....

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Identifiers

PMID: 28095483
DOI: 10.1371/journal.pone.0169516
PMCID: PMC5240939

Genes

ICAM1
NKAPL
ABO
CDH13
IKBKE
NFKB1
PDCD11
PRKCB
RELA
TNFAIP3

Provenance

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