Article
Association study of Nogo-related genes with schizophrenia in a Japanese case-control sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2011
Jitoku Daisuke, Hattori Eiji, Iwayama Yoshimi, Yamada Kazuo, Toyota Tomoko, Kikuchi Mitsuru, Maekawa Motoko, Nishikawa Toru, Yoshikawa Takeo
Abstract excerpt
Many studies have suggested that myelin dysfunction may be causally involved in the pathogenesis of schizophrenia. Nogo (RTN4), myelin-associated glycoprotein (MAG) and oligodendrocyte myelin glycoprotein (OMG) all bind to the common receptor, Nogo-66 receptor 1 (RTN4R). We examined 68 single nucleotide polymorphisms (SNPs) (51 with genotyping and 17 with imputation analysis) from these four genes for genetic...
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