Article
Developmental expression of glutamic acid decarboxylase and of gamma-aminobutyric acid type B receptors in the ascidian Ciona intestinalis.
The Journal of comparative neurology - 20 Jan 2008
Zega Giuliana, Biggiogero Maira, Groppelli Silvia, Candiani Simona, Oliveri Diana, Parodi Manuela, Pestarino Mario, De Bernardi Fiorenza, Pennati Roberta
Abstract excerpt
We describe Ciona intestinalis gamma-aminobutyric acid (GABA)-ergic neurons during development, studying the expression pattern of Ci-GAD (glutamic acid decarboxylase: GABA synthesizing enzyme) by in situ hybridization. Moreover, we cloned two GABA(B) receptor subunits (Ci-GABA(B)Rs), and a phylogenetic analysis (neighbor-joining method) suggested that they clustered with their vertebrate counterparts. We...
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