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Article

Genes required for GABA function in Caenorhabditis elegans.

Nature - 22 Jul 1993

McIntire S L, Jorgensen E, Horvitz H R

Abstract excerpt

gamma-Aminobutyric acid (GABA) neurotransmission is widespread in vertebrate and invertebrate nervous systems. Here we use a genetic approach to identify molecules specific to GABA function. On the basis of the known in vivo roles of GABAergic neurons in controlling behaviour of the nematode Caenorhabditis elegans, we identified mutants defective in GABA-mediated behaviours. Five genes are necessary either for...

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PMID: 8332190
DOI: 10.1038/364334a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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