Article
Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.
Journal of bacteriology - 1 Feb 2008
Higashi Kyohei, Ishigure Hiroyuki, Demizu Risa, Uemura Takeshi, Nishino Kunihiko, Yamaguchi Akihito, Kashiwagi Keiko, Igarashi Kazuei
Abstract excerpt
A spermidine excretion protein in Escherichia coli was looked for among 33 putative drug exporters thus far identified. Cell toxicity and inhibition of growth due to overaccumulation of spermidine were examined in an E. coli strain deficient in spermidine acetyltransferase, an enzyme that metabolizes spermidine. Toxicity and inhibition of cell growth by spermidine were recovered in cells transformed with pUCmdtJI...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
