Article
A985G polymorphism of the endothelin-2 gene and atrial fibrillation in patients with hypertrophic cardiomyopathy.
Circulation journal : official journal of the Japanese Circulation Society - 1 Dec 2007
Nagai Takayuki, Ogimoto Akiyoshi, Okayama Hideki, Ohtsuka Tomoaki, Shigematsu Yuji, Hamada Mareomi, Miki Tetsuro, Higaki Jitsuo
Abstract excerpt
BACKGROUND: It was recently suggested that the angiotensin-converting enzyme insertion/insertion genotype, which is considered to be protective against cardiovascular disease, was a significant risk factor for atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to investigate the association between the endothelin-2 (EDN2) A985G polymorphism and AF in patients...
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