Article
Protective effect of the 1742(C/G) polymorphism of human cardiotrophin-1 against left ventricular hypertrophy in essential hypertension.
Journal of hypertension - 1 Nov 2010
Robador Pablo A, Moreno María U, Beloqui Oscar, Varo Nerea, Redón Josep, Fortuño Ana, Zalba Guillermo, Díez Javier
Abstract excerpt
OBJECTIVE: Experimental and clinical evidence supports a role of cardiotrophin-1 (CT-1) in the development of hypertensive left ventricular hypertrophy (LVH). The goal of this study was to investigate the relationship between human CT-1 genetic background and LVH in essential hypertension. METHODS: A total of 900 individuals were genotyped for the 1742(C/G) polymorphism of the human CT-1 gene. Serum CT-1 levels...
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