Article
Variation in the mutation frequency determining quinolone resistance in Chlamydia trachomatis serovars L2 and D.
The Journal of antimicrobial chemotherapy - 1 Jan 2008
Rupp Jan, Solbach Werner, Gieffers Jens
Abstract excerpt
OBJECTIVES: Quinolone resistance of chlamydiae is supposed to be extremely rare. To assess the risk for the emergence of chlamydial quinolone resistance, we analysed the occurrence of resistant mutants in a quantitative perspective. METHODS: Infectious elementary bodies of Chlamydia trachomatis serovar L(2) (ATCC VR-902B) and D (ATTC VR-885) clones were purified on density gradients, and mutants resistant to...
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