Article
Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides.
Antimicrobial agents and chemotherapy - 1 Apr 2004
Misyurina O Y, Chipitsyna E V, Finashutina Y P, Lazarev V N, Akopian T A, Savicheva A M, Govorun V M
Abstract excerpt
For six clinical isolates of Chlamydia trachomatis, in vitro susceptibility to erythromycin, azithromycin, and josamycin has been determined. Four isolates were resistant to all the antibiotics and had the mutations A2058C and T2611C (Escherichia coli numbering) in the 23S rRNA gene. All the isol...
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