Article
Molecular characterization of the Rocky Mountain elk (Cervus elaphus nelsoni) PRNP putative promoter.
The Journal of heredity - 1 Jan 2000
Seabury Christopher M, Gill Clare A, Templeton Joe W, Dyar Joseph B, Derr James N, Adelson David L, Owens Elaine, Davis Donald S, Kraemer Duane C, Womack James E
Abstract excerpt
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting deer (Odocoileus spp.), moose (Alces alces), and Rocky Mountain elk (Cervus elaphus nelsoni). Leucine homozygosity at elk PRNP codon 132 has been associated with reduced CWD susceptibility. However, naturally acquired CWD has been detected in elk possessing the 132 Leu/Leu genotype. Recent human and bovine studies indicate...
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