Article
Pathogen-mediated selection in free-ranging elk populations infected by chronic wasting disease.
Proceedings of the National Academy of Sciences of the United States of America - 14 Nov 2017
Monello Ryan J, Galloway Nathan L, Powers Jenny G, Madsen-Bouterse Sally A, Edwards William H, Wood Mary E, O'Rourke Katherine I, Wild Margaret A
Abstract excerpt
Pathogens can exert a large influence on the evolution of hosts via selection for alleles or genotypes that moderate pathogen virulence. Inconsistent interactions between parasites and the host genome, such as those resulting from genetic linkages and environmental stochasticity, have largely prevented observation of this process in wildlife species. We examined the prion protein gene (PRNP) in North American elk...
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