Article
Geographic variation in the PRNP gene and its promoter, and their relationship to chronic wasting disease in North American deer.
Prion - 1 Dec 2020
Zink Robert M, Najar Nadje, Vázquez-Miranda Hernán, Buchanan Brittaney L, Loy Duan, Brodersen Bruce W
Abstract excerpt
PRNP genotypes, number of octarepeats (PHGGGWGQ) and indels in the PRNP promoter can influence the progression of prion disease in mammals. We found no relationship between presence of promoter indels in white-tailed deer and mule deer from Nebraska and CWD presence. White-tailed deer with the 95 H allele and G20D mule deer were more likely to be CWD-free, but unlike other studies white-tailed deer with the 96S...
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