PRNP variant frequencies in Roosevelt and Rocky Mountain elk (Cervus canadensis) from Oregon and their implications for chronic wasting disease.

Abstract excerpt

Chronic wasting disease (CWD) is a fatal disease in cervids caused by abnormally folded proteins known as prions. Since its identification in 1967, CWD has spread to wild cervid populations in 36 US states. Some variants in the prion protein gene (PRNP) are known to confer advantages against prion diseases in many species including cervids. In elk (Cervus canadensis), a non-synonymous mutation in PRNP is...

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• Deer
• Gene Frequency
• PRNP gene
• Genetic Variation
• Oregon