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Article

Association of interferon gamma and interleukin 10 genes with tuberculosis in Hong Kong Chinese.

Genes and immunity - 1 Jun 2005

Tso H W, Ip W K, Chong W P, Tam C M, Chiang A K S, Lau Y L

Abstract excerpt

Interferon gamma (IFN-gamma) and interleukin 10 (IL-10) are believed to play opposing roles in host immunity against mycobacterial infection. IFN-gamma activates macrophages, while IL-10 downregulates the expression of T helper type 1 cytokines, MHC class II antigens and costimulatory molecules on macrophages. Associations of IFN-gamma -179 (G/T), +874 (A/T), +875 miscrosatellite CA repeats and +4766 (C/T), and...

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Source

Identifiers

PMID: 15815688
DOI: 10.1038/sj.gene.6364189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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