Article
A survey of current methods to detect and genotype inversions.
Human mutation - 1 Nov 2022
Hanlon Vincent C T, Lansdorp Peter M, Guryev Victor
Abstract excerpt
Polymorphic inversions are ubiquitous in humans and they have been linked to both adaptation and disease. Following their discovery in Drosophila more than a century ago, inversions have proved to be more elusive than other structural variants. A wide variety of methods for the detection and genotyping of inversions have recently been developed: multiple techniques based on selective amplification by PCR, short-...
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