Article
Bone marrow microvessel density in chronic myeloproliferative disorders: a study of 115 patients with clinicopathological and molecular correlations.
British journal of haematology - 1 Jan 2008
Boveri Emanuela, Passamonti Francesco, Rumi Elisa, Pietra Daniela, Elena Chiara, Arcaini Luca, Pascutto Cristiana, Castello Alessandro, Cazzola Mario, Magrini Umberto, Lazzarino Mario
Abstract excerpt
Philadelphia-negative chronic myeloproliferative disorders (CMD) include polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). Angiogenesis is critical in the pathogenesis of PMF. We studied angiogenesis in 115 patients with CMD (23 PV, 24 ET, 46 PMF, 12 post-PV and 10 post-ET myelofibrosis) by assessment of microvessel density (MVD) in bone marrow (BM). Kruskall-Wallis analysis...
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