Article
Circulating Cd34+ cell count differentiates primary myelofibrosis from other Philadelphia-negative myeloproliferative neoplasms: a pragmatic study.
Annals of hematology - 1 Oct 2016
Orvain C, Luque Paz D, Dobo I, Cottin L, Le Calvez G, Chauveau A, Mercier M, Farhi J, Boyer F, Ianotto J C, Guibourg B, Rousselet M C, Zandecki M, Ifrah N, Hunault-Berger M, Ugo V, Genevieve F
Abstract excerpt
A high number of circulating CD34+ cells has been advocated to distinguish primary myelofibrosis from other Philadelphia-negative myeloproliferative neoplasms. We re-evaluated the diagnostic interest of measuring circulating CD34+ cells in 26 healthy volunteers and 256 consecutive patients at diagnosis for whom a myeloproliferative neoplasm was suspected. The ROC curve analysis showed that a number of CD34+...
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