Article
Angiogenesis and vascular endothelial growth factor-/receptor expression in myeloproliferative neoplasms: correlation with clinical parameters and JAK2-V617F mutational status.
British journal of haematology - 1 Jul 2009
Medinger Michael, Skoda Radek, Gratwohl Alois, Theocharides Alexandre, Buser Andreas, Heim Dominik, Dirnhofer Stephan, Tichelli André, Tzankov Alexandar
Abstract excerpt
Data on angiogenesis in the bone marrow of BCR-ABL1-negative myeloproliferative neoplasm (MPN) patients suggest an increase of the microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression, but relations to the JAK2-V617F status remain controversial. We performed immunohistochemical studies of MVD and VEGF-expression in 100 MPN, including 24 essential thrombocythemia- (ET), 46...
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