Article
Impairment of cobalt-induced riboflavin biosynthesis in a Debaryomyces hansenii mutant.
Canadian journal of microbiology - 1 Nov 2007
Seda-Miró Jasmine M, Arroyo-González Nancy, Pérez-Matos Ana, Govind Nadathur S
Abstract excerpt
Flavinogenic yeasts such as Debaryomyces hansenii overproduce riboflavin (RF) in the presence of heavy metals. Growth and RF production were compared between wild-type D. hansenii and a RF production-impaired metal-tolerant ura3 mutant in the presence of sublethal cobalt(II) concentrations. Debaryomyces hansenii (wild type) exhibits an extended lag phase with an increase in RF synthesis. Supplementation of...
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