Article
A single-nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances bladder cancer susceptibility.
BJU international - 1 Feb 2008
Tasci Ali I, Tugcu Volkan, Ozbek Emin, Ozbay Bedi, Simsek Abdulmuttalip, Koksal Vedat
Abstract excerpt
OBJECTIVE: To explore the association between the promoter polymorphism (that influences the transcriptional level) of matrix metalloproteinase-1 (MMP-1, associated with tumour cell invasion and metastasis) and bladder cancer in a Turkish population. PATIENTS, SUBJECTS AND METHODS: The MMP-1 polymorphism was assessed in 102 transitional cell carcinomas of the bladder (50 Ta, 52 T2-4) and in 94 age-, smoking- and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
