Article
Impact of interleukin-10 polymorphisms (-1082 and -3575) on the survival of patients with lymphoid neoplasms.
Haematologica - 1 Nov 2007
Domingo-Domènech Eva, Benavente Yolanda, González-Barca Eva, Montalban Carlos, Gumà Josep, Bosch Ramón, Wang Sophia S, Lan Qing, Whitby Denise, Fernández de Sevilla Alberto, Rothman Nathaniel, de Sanjosé Sílvia
Abstract excerpt
BACKGROUND AND OBJECTIVES: Single-nucleotide polymorphisms (SNP) in interleukin-10 (IL-10) genes can influence immune responses, which may affect the outcome of patients with lymphoid neoplasms. The aim of this study was to explore the association between polymorphisms of IL-10-(1082A>G) and IL-10-(3575T>A) with the overall survival in patients with lymphoid neoplasms. DESIGN AND METHODS: We analyzed two IL-10...
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