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Article

Interleukin-10 gene polymorphisms are associated with freedom from treatment failure for patients with Hodgkin lymphoma.

The oncologist - 1 Jan 2013

Schoof Nils, Franklin Jeremy, Fürst Robert, Zander Thomas, von Bonin Frederike, Peyrade Frederic, Trümper Lorenz, Diehl Volker, Engert Andreas, Kube Dieter, Re Daniel

Abstract excerpt

BACKGROUND: Hodgkin lymphoma (HL) is a lymphoid malignancy characterized by the production of various cytokines possibly involved in immune deregulation. Interleukin-10 (IL-10) serum levels have been associated with clinical outcome in patients with HL. Because host genetic variations are known to alter the expression and function of cytokines and their receptors, we investigated whether genetic variations...

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Identifiers

PMID: 23299779
DOI: 10.1634/theoncologist.2012-0291
PMCID: PMC3556261

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