Article
Interleukin-10 gene polymorphism influences the prognosis of T-cell non-Hodgkin lymphomas.
British journal of haematology - 1 May 2007
Lee Je-Jung, Kim Dong Hwan, Lee Nan Young, Sohn Sang Kyun, Kim Jong Gwang, Kim Hyeoung-Joon, Do Young Rok, Park Yeon Hee
Abstract excerpt
Interleukin-10 (IL-10) is one of the cytokines implicated in the pathogenesis of diffuse large B-cell lymphoma (DLBCL) in which it acts as auto/paracrine growth factor for lymphoma growth. T-cell non-Hodgkin lymphoma (NHL) is a heterogeneous disease, the biological basis of which is not fully understood. Some evidence suggests that IL-10 might be associated with the progression of T-cell NHLs and that IL-10 may...
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