Article
Clonal relationship between Hashimoto thyroiditis and thyroid lymphoma
15 Nov 2007
Abstract excerpt
BACKGROUND: Although Hashimoto thyroiditis (HT) is a predisposing factor for B-lineage thyroid lymphoma, clonal B-cell populations in HT are rare. AIM: To investigate whether there is a clonal relationship between HT and primary thyroid lymphoma. METHODS: Clonalilty and sequence similarity was determined by PCR followed by sequencing and comparing immunoglobulin heavy chain (IgH) gene rearrangement sequences to...
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