Wotherspoon criteria combined with B cell clonality analysis by advanced polymerase chain reaction technology discriminates covert gastric marginal zone lymphoma from chronic gastritis

Abstract excerpt

BACKGROUND AND AIMS: Gastric mucosa associated lymphoid tissue lymphoma is a well defined B cell lymphoma yet often impossible to distinguish from severe chronic gastritis on morphological grounds alone. Therefore, it was suggested to use the clonality of the immunoglobulin (Ig) heavy chain (H) genes, as detected by polymerase chain reaction (PCR), as a decisive criterion. However, there is controversy as to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Celiac Disease Research and Management
• Share to Lymphoma Diagnosis and Treatment
• Share to Monoclonal and Polyclonal Antibodies Research