Article
Haplotype evolution of SLITRK1, a candidate gene for Gilles de la Tourette syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008
Speed William C, O'Roak Brian J, Tárnok Zsanett, Barta Csaba, Pakstis Andrew J, State Matthew W, Kidd Kenneth K
Abstract excerpt
Gilles de la Tourette syndrome (GTS) is a complex disorder with a clear genetic component but no clearly identified genes with variation of etiologic relevance. Various candidate regions and genes show some evidence of affecting risk, though clearly not all patients/families can be explained by any one of them. Resequencing one candidate gene, SLITRK1, has identified four new variants. Including them, we have...
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