Article
Sequence variants in SLITRK1 are associated with Tourette's syndrome.
Science (New York, N.Y.) - 14 Oct 2005
Abelson Jesse F, Kwan Kenneth Y, O'Roak Brian J, Baek Danielle Y, Stillman Althea A, Morgan Thomas M, Mathews Carol A, Pauls David L, Rasin Mladen-Roko, Gunel Murat, Davis Nicole R, Ercan-Sencicek A Gulhan, Guez Danielle H, Spertus John A, Leckman James F, Dure Leon S, Kurlan Roger, Singer Harvey S, Gilbert Donald L, Farhi Anita, Louvi Angeliki, Lifton Richard P, Sestan Nenad, State Matthew W
Abstract excerpt
Tourette's syndrome (TS) is a genetically influenced developmental neuropsychiatric disorder characterized by chronic vocal and motor tics. We studied Slit and Trk-like 1 (SLITRK1) as a candidate gene on chromosome 13q31.1 because of its proximity to a de novo chromosomal inversion in a child wit...
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