Article
Analysis of SLITRK1 in Japanese patients with Tourette syndrome using a next-generation sequencer.
Psychiatric genetics - 1 Dec 2015
Inai Aya, Tochigi Mamoru, Kuwabara Hitoshi, Nishimura Fumichika, Kato Kayoko, Eriguchi Yosuke, Shimada Takafumi, Furukawa Masaomi, Kawamura Yoshiya, Sasaki Tsukasa, Kakiuchi Chihiro, Kasai Kiyoto, Kano Yukiko
Abstract excerpt
The SLITRK1 (Slit and Trk-like 1) gene has been suggested to be a promising candidate for Tourette syndrome (TS) since the first report that identified its two rare variants adjacent to the chromosome inversion in a TS child with inv(13) (q31.1;q33.1). A series of replication studies have been carried out, whereas the role of the gene has not been elucidated. The present study aimed to determine whether the two...
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