Article
The eIF4G homolog DAP5/p97 supports the translation of select mRNAs during endoplasmic reticulum stress
13 Nov 2007
Abstract excerpt
DAP5/p97 is a member of the eIF4G family of translation initiation factors that has been suggested to play an important role in the translation of select messenger RNA molecules. We have shown previously that the caspase-cleaved form of DAP5/p97, termed p86, is required for the induction of the endoplasmic reticulum (ER)-stress-responsive internal ribosome entry site (IRES) of the caspase inhibitor HIAP2. We show...
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