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Article

Association between the 1858T allele of the protein tyrosine phosphatase nonreceptor type 22 and type 1 diabetes in a Brazilian population.

Tissue antigens - 1 Aug 2010

Chagastelles P C, Romitti M, Trein M R, Bandinelli E, Tschiedel B, Nardi N B

Abstract excerpt

The 1858T allele of the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene has been associated to diabetes in different populations. We investigated a possible relationship between this polymorphism and type 1 diabetes in a cohort of Brazilian patients. A significantly higher frequency of the 1858T allele was observed in diabetic patients (n = 211) than in control individuals (n = 241). Additionally, the...

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Source

Identifiers

PMID: 20331840
DOI: 10.1111/j.1399-0039.2010.01480.x

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between the 1858T allele of the protein tyrosine phosphatase nonreceptor type 22 and type 1 diabetes in a Brazilian population.PMID 20331840Read ↗

Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Semantic proximity Read ↗

The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population.Semantic proximity Read ↗

Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population.Semantic proximity Read ↗

The role of PTPN22 C1858T gene polymorphism in diabetes mellitus type 1: first evaluation in Greek children and adolescents.Semantic proximity Read ↗

Association of PTPN22+1858C/T polymorphism with Type 1 diabetes in the North Indian population.Semantic proximity Read ↗

Population-based and family-based studies on the protein tyrosine phosphatase non-receptor 22 gene polymorphism and type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Semantic proximity Read ↗

Association of PTPN22 C1858T polymorphism and type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

The Potential Role of PTPN-22 C1858T Gene Polymorphism in the Pathogenesis of Type 1 Diabetes in Saudi Population.Semantic proximity Read ↗

Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes.Semantic proximity Read ↗

Association of the PTPN22 gene (+1858C/T, -1123G/C) polymorphisms with type 1 diabetes mellitus: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of PTPN22 gene polymorphism with type 1 diabetes mellitus in Chinese children and adolescents.Semantic proximity Read ↗

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