Article
The Trp64Arg polymorphism of the beta3-adrenergic receptor gene is associated with increased small dense low-density lipoprotein in a rural Japanese population: the Mima study.
Metabolism: clinical and experimental - 1 Dec 2007
Tsuzaki Kokoro, Kotani Kazuhiko, Fujiwara Shinji, Sano Yoshiko, Matsuoka Yukiyo, Domichi Masayuki, Hamada Taku, Shimatsu Akira, Sakane Naoki
Abstract excerpt
The presence of small dense low-density lipoprotein (sdLDL) is closely associated with an increased risk of developing coronary artery disease. The Trp64Arg polymorphism of the beta(3)-adrenergic receptor (beta(3)-AR) gene is a genetic marker for obesity-related traits. However, any possible association between this polymorphism and sdLDL profiles is unclear. The objective of this study is to investigate the...
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