Article
Successful genome-wide scan in paired blood and buccal samples.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2007
Feigelson Heather Spencer, Rodriguez Carmen, Welch Robert, Hutchinson Amy, Shao Wen, Jacobs Kevin, Diver W Ryan, Calle Eugenia E, Thun Michael J, Hunter David J, Thomas Gilles, Chanock Stephen J
Abstract excerpt
Interest in genome-wide association studies to identify susceptibility alleles for cancer is growing, and several are currently planned or under way. Although the feasibility of collecting buccal cell samples as an alternative to venous blood samples as a source of genomic DNA has been shown, the validity of using DNA from buccal cells for genome-wide scans has not been assessed. We used 46 paired buffy coat and...
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