No association between Cholinergic Muscarinic Receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples.

doi:10.1007/s10519-009-9274-z

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Article

No association between Cholinergic Muscarinic Receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples.

Behavior genetics - 1 Sept 2009

Lind Penelope A, Luciano Michelle, Horan Michael A, Marioni Riccardo E, Wright Margaret J, Bates Timothy C, Rabbitt Patrick, Harris Sarah E, Davidson Yvonne, Deary Ian J, Gibbons Linda, Pickles Andrew, Ollier William, Pendleton Neil, Price Jackie F, Payton Antony, Martin Nicholas G

Abstract excerpt

Cognitive ability has a substantial genetic component and more than 15 candidate genes have been identified over the past 8 years. One gene that has been associated with general cognitive ability is the cholinergic muscarinic 2 receptor (CHRM2). In an attempt to replicate this finding we typed marker rs8191992 (the originally reported CHRM2 SNP) in two population based cohorts-one Scottish aged over 50 years (N =...

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PMID: 19418213
DOI: 10.1007/s10519-009-9274-z

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CHRM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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