Article
Unbiased analysis, enrichment and purification of thymic stromal cells.
Journal of immunological methods - 1 Jan 2008
Gray Daniel H D, Fletcher Anne L, Hammett Maree, Seach Natalie, Ueno Tomoo, Young Lauren F, Barbuto Jade, Boyd Richard L, Chidgey Ann P
Abstract excerpt
The microenvironment of the thymus consists of functionally discrete niches composed of distinct stromal cell subsets. Clinically relevant changes affecting T-cell differentiation occur within these niches with age and injury caused by irradiation and chemotherapy treatments. The study of thymic stromal cells has been hampered by the technical difficulty in isolating significant numbers of this important...
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