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Article

Optimizing separation efficiency of 2-DE procedures for visualization of different superoxide dismutase forms in a cellular model of amyotrophic lateral sclerosis.

Electrophoresis - 1 Dec 2007

Di Poto Cristina, Iadarola Paolo, Salvini Roberta, Passadore Ileana, Cereda Cristina, Ceroni Mauro, Bardoni Anna Maria

Abstract excerpt

Neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease (PD) have been associated with increased production of reactive oxygen species. In AD and PD patients, superoxide dismutase (SOD1) was also indicated as a major target of oxidative damage. In particular, in brain tissue of these patients, different SOD1 isoforms have been identified, although their functional role still remains to be...

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Source

Identifiers

PMID: 17987632
DOI: 10.1002/elps.200700162

Genes

SOD1
SDS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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