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Article

Muscle cells and motoneurons differentially remove mutant SOD1 causing familial amyotrophic lateral sclerosis.

Journal of neurochemistry - 1 Jul 2011

Onesto Elisa, Rusmini Paola, Crippa Valeria, Ferri Nicola, Zito Arianna, Galbiati Mariarita, Poletti Angelo

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal motoneuronal disease which occurs in sporadic or familial forms, clinically indistinguishable. About 15% of familial ALS cases are linked to mutations of the superoxide dismutase 1 (SOD1) gene that may induce misfolding in the coded protein, exerting...

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Source

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Identifiers

PMID: 21554318
DOI: 10.1111/j.1471-4159.2011.07298.x
PMCID: PMC3206220

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21554318-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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