Article
The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levels.
BJU international - 1 Feb 2008
Severi Gianluca, Hayes Vanessa M, Tesoriero Andrea A, Southey Melissa C, Hoang Hoa N, Padilla Emma J D, Morris Howard A, English Dallas R, Sutherland Robert L, Boyle Peter, Hopper John L, Giles Graham G
Abstract excerpt
OBJECTIVE: To use a large population-based case-control study to test the association between the common genetic variant rs743572 (-34 T to C), prostate cancer risk and circulating levels of several hormones. SUBJECTS AND METHODS: A previous meta-analysis concluded that reported associations between rs743572 in the promoter of CYP17A1 and prostate cancer risk might reflect publication bias, but a few recent...
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