Article
+61A>G polymorphism in the EGF gene does not increase the risk of lung cancer.
Respirology (Carlton, Vic.) - 1 Nov 2007
Kang Hyo-Gyoung, Choi Jin Eun, Lee Won Kee, Kam Sin, Cha Sung Ick, Kim Chang Ho, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
BACKGROUND AND OBJECTIVES: Epidermal growth factor (EGF) plays an important role in tumourigenesis by binding with its receptor, EGFR. Variations in the DNA sequence in the EGF gene can lead to an alteration in EGF production and/or activity, which can affect an individual's susceptibility to lung cancer. To test this hypothesis, this study examined the association between the +61 A>G polymorphism in the...
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