Article
Association between EGF +61 genetic polymorphisms and non-small cell lung cancer increased risk in a Portuguese population: a case-control study.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2012
de Mello Ramon Andrade, Ferreira Mónica, Costa Sandra, Costa Bruno Marques, Pires Filipa Soares, Neves Inês, Almeida Maria Inês, Cunha João, Oliveira Pedro, Hespanhol Venceslau, Reis Rui Manuel
Abstract excerpt
Epidermal growth factor (EGF) and its receptor play critical roles in non-small cell lung cancer (NSCLC) carcinogenesis. A functional polymorphism in the EGF gene has been linked to increased cancer susceptibility. This study aimed to evaluate the role of the EGF +61A/G polymorphism as risk facto...
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