Article
Exploring first-degree family history in a cohort of Portuguese Alzheimer's disease patients: population evidence for X-chromosome linked and recessive inheritance of risk factors.
Journal of neurology - 1 Oct 2024
Tábuas-Pereira Miguel, Bernardes Catarina, Durães João, Lima Marisa, Nogueira Ana Rita, Saraiva Jorge, Tábuas Teresa, Coelho Mariana, Paquette Kimberly, Westra Kaitlyn, Kun-Rodrigues Célia, Almeida Maria Rosário, Baldeiras Inês, Brás José, Guerreiro Rita, Santana Isabel
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) heritability is estimated to be around 70-80%. Yet, much of it remains to be explained. Studying transmission patterns may help in understanding other factors contributing to the development of AD. OBJECTIVE: In this study, we aimed to search for evidence of autosomal recessive or X- and Y-linked inheritance of risk factors in a large cohort of Portuguese AD patients. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.